Review of DHH-B supplement

DHH-B review

Dihydrohonokiol-B or DHH-B supplement is a powerful extract from Magnolia Bark with a concentrated dosage of its active ingredient honokiol. Тhis is a bioactive compound that has been shown to produce an anti-anxiety effect without impacting motor skills or respiration.  It decreases daytime anxiety, provides better sleep and reduces stress.

DHH-B is a supplement with a high dosage of honokiol with 20x stronger properties than standard Magnolia supplements. DHH-B extracted from Magnolia provides relaxation and better sleep in similar mechanism as benzodiazepines but without side effects such as decreased motor function and respiration.

Table of Contents

Mechanism of Action

Magnolia is a tree that is native to China and it has an ancient history as a therapeutic compound used to treat anxiety and sleep deprivation. Magnolia Bark has several compounds with anti-bacterial and anti-inflammatory properties, but the most-well studied is the compound honokiol. It works as an anxiolytic – it helps you lower anxiety and reduce stress.

If you are concerned about addiction and excessive sedation from medications, DHH-B will provide you with a safer alternative than prescribed medications.

 Increases GABA activity

Gamma-aminobutyric acid (GABA) is a neurotransmitter that exerts a calming effect. It blocks or inhibits certain brain signals and decreases activity in your nervous system. When GABA attaches to a protein in your brain known as a GABA receptor, it produces a calming effect. This can help with feelings of anxiety, stress, and fear. DHH-B s will increase the activity of GABA neurotransmitter.

Anti-oxidative properties

Magnolia Bark extracts show strong anti-oxidative properties and block oxidative stress in the body. Oxidative stress means massive production of free radicals in the body which leads to chain chemical reactions making an impact to your physical and mental health. Magnolia Blank increases your levels of antioxidants and decreases production of free radicals in your body.

Activates Cannabinoid Receptors

DDH-B can activate cannabinoid receptors located throughout the body. Activation of these receptors in the body will help you relieve pain and elevate mood in a way similar to CBD.

Inhibits stress hormone production

Active compounds found in Magnolia supplements can reduce adrenaline, a hormone associated with stress. Magnolia can also reduce cortisol production, another stress-related hormone. These hormones are associated with adrenal fatigue – term used to describe group of symptoms such as anxiety, insomnia and fatigue.

Benefits of DHH-B

According to research, honokiol shows similar effects as benzodiazepine drugs in relieving anxiety. Results can vary, however, based on the magnolia bark extract used. Honokiol (DHH-B) and magnolol from Magnolia extract have been found most effective in treating insomnia, stress, depression and other mood-related disorders.

Better sleep

DHH-B benefits better sleep

It works effectively as a sleep promoter, thanks to its natural ability to relax both mind and body. As mentioned before, DDH-B can boost GABA activity which also leads to better sleep. In fact, according to some studies, it will increase the time you spend in REM sleep and also reduce the time it takes you to fall asleep.

Its ability to decrease the production of stress hormones such as cortisol and adrenaline makes DDH-B effective sleep aid for people who are anxious and stressed.

Fights Stress and Anxiety

anxiety and stress relief DHH-B

Increasing GAMA activity isn’t only important for better sleep, but it also works as a mood booster. Studies show that honokiol can treat anxiety effectively like diazepam but without affecting your motor or cognitive skills.

Also, one of the benefits of this product is that it won’t cause addiction or side effects. 

Brain Health

brain health DHH-B


As said before, DHH-B has the antioxidative ability and ability to activate GAMA receptors. Both of these properties are essential to your brain health. Antioxidative properties of the product will prevent your brain cells from damaging.

One important benefit of the product is that it can help maintain levels of acetylcholine, a neurotransmitter that strengthens and weakens the signals between neurons responsible for our memory and focus. Reduced levels of acetylcholine are typically found in people with Alzheimer’s disease.

Anti-inflamatory and pain-reducing properties

Honokiol has been recognized in traditional natural medicine as an effective treatment for pain relief. It has anti-inflammatory properties and it can reduce pain caused by inflammation. DDH-B supplement will serve you as a source of pain relief and it will help you alleviate pain.

DDH-B: Are There Any Side Effects?

According to research, DDH-B is fairly well tolerated with limited side effects.  However, it is recommended to being with the low dosage and then gradually increase, to see your body’s response to the product.

Some of the found side effects include headache and dizziness. If you are pregnant or breastfeeding, consider consulting with your healthcare provider before using DHH-B or any other Magnolia based supplements.

You should also avoid combining DDH-B with alcohol, as it can cause sleepiness and affect your motor skills. This is typical when consuming larger doses of the supplement.

Interaction with other medications

DHH-B supplement

There are some of the commonly used medications and supplements with identified interactions with DHH-B as well as other supplements containing honokiol. These include anticoagulant medications and sedative medications such as benzodiazepines, CNS depressants, barbiturates.

A combination of DDH-B with some herbs and supplements can cause excessive sleepiness. Such herbs and supplementation include Valerian, 5-HTP, Yerba Mansa.

In general terms, DDH-B appears to be fairly well tolerated among humans. However, If you have any doubts or considerations, consult with your practitioner before.

DDH-B user reviews

We’ve looked through the user reviews of the product. Most of the users found DDH-B supplement useful as they claim their anxiety is reduced and their sleep quality is better. However, this product seems not to be working on everyone. Some of the users claim they haven’t noticed a significant improvement in the way they feel. Worth mentioning is that none of them noted side effects or addition to the product.

However, we must underline the fact that DDH-B is a natural supplement with bioactive ingredients extracted from Magnolia bark. Therefore, it might take some time before you notice notable results.

Some of the reviews that we found on Amazon:

“This gave me such a fast & effective sense of calm… If you have a dependency on Xanax, this is a remarkable natural replacement. I suffer from social anxiety, occasional full out panic attacks, and insomnia. I have not had a panic attack since purchasing this product but there was no help with sleep. “

I have had sleeping issues for a long time. I take two of these 30 minutes, I can’t keep my eyes open! I get better quality sleep as well. This is my 3rd bottle and I will be a lifetime customer!”


Positive and negative sides of the product

Every product has its positive and negatives sides. In general terms, people didn’t have a bad experience with this product and it showed highly effective in treating sleep problems, anxiety and stress.

Positive sides of the DHH-B

-it offers a safer alternative to benzodiazepines

-doesn’t cause addiction and side effects characteristic to benzodiazepines

-it offers a natural way to relax and stay focused during the day

-natural sedative effect

– long-term results

Negative sides of the DHH-B

-Results can vary from person to person

-Limited research on side effects

-it might take some time to kick in

A final word on the product

DHH-B supplements showed to be a suitable replacement for prescribed medications such as Xanax or Valium. Compared to the other honokiol (Magnolia) based supplements, DHH-B showed more notable affect due to its high levels of honokiol. As this is a natural supplement, it might take some time before you notice desired effects, but it compensates for long-term results. Also, compared to benzodiazepines it won’t cause you sleepiness and disturb your motor skills during the day.

If you struggle with anxiety attacks and sleeping problems, you might want to look for safer alternatives such as DHH-B. This supplement offers a natural way to rest, relax and stay sharp and focused, all at the same time.


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